The Small GTPase Arf1 Modulates Arp2/3-Mediated Actin Polymerization via PICK1 to Regulate Synaptic Plasticity

Inhibition of Arp2/3-mediated actin polymerization by PICK1 is a central mechanism to AMPA receptor (AMPAR) internalization and long-term depression (LTD), although the signaling pathways that modulate this process in response to NMDA receptor (NMDAR) activation are unknown. Here, we define a functi...

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Detalles Bibliográficos
Autores principales: Rocca, Daniel L., Amici, Mascia, Antoniou, Anna, Suarez, Elena Blanco, Halemani, Nagaraj, Murk, Kai, McGarvey, Jennifer, Jaafari, Nadia, Mellor, Jack R., Collingridge, Graham L., Hanley, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725416/
https://www.ncbi.nlm.nih.gov/pubmed/23889934
http://dx.doi.org/10.1016/j.neuron.2013.05.003

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