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Using a multi-staged strategy based on machine learning and mathematical modeling to predict genotype-phenotype risk patterns in diabetic kidney disease: a prospective case–control cohort analysis
BACKGROUND: Multi-causality and heterogeneity of phenotypes and genotypes characterize complex diseases. In a database with comprehensive collection of phenotypes and genotypes, we compared the performance of common machine learning methods to generate mathematical models to predict diabetic kidney...
Autores principales: | Leung, Ross KK, Wang, Ying, Ma, Ronald CW, Luk, Andrea OY, Lam, Vincent, Ng, Maggie, So, Wing Yee, Tsui, Stephen KW, Chan, Juliana CN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726338/ https://www.ncbi.nlm.nih.gov/pubmed/23879411 http://dx.doi.org/10.1186/1471-2369-14-162 |
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