Mechanistic Insights into the Neutralization of Cytotoxic Abrin by the Monoclonal Antibody D6F10

Abrin, an A/B toxin obtained from the Abrus precatorius plant is extremely toxic and a potential bio-warfare agent. Till date there is no antidote or vaccine available against this toxin. The only known neutralizing monoclonal antibody against abrin, namely D6F10, has been shown to rescue the toxici...

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Detalles Bibliográficos
Autores principales: Bagaria, Shradha, Ponnalagu, Devasena, Bisht, Shveta, Karande, Anjali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726390/
https://www.ncbi.nlm.nih.gov/pubmed/23922965
http://dx.doi.org/10.1371/journal.pone.0070273

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