Cargando…

Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish

BACKGROUND: NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of all mature hormone producing cells. It is repressed by Notch signaling that prevents pancreatic cell differentiation by maintaining precursors in an undifferentiated state. R...

Descripción completa

Detalles Bibliográficos
Autores principales: Flasse, Lydie C, Pirson, Justine L, Stern, David G, Von Berg, Virginie, Manfroid, Isabelle, Peers, Bernard, Voz, Marianne L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726459/
https://www.ncbi.nlm.nih.gov/pubmed/23835295
http://dx.doi.org/10.1186/1741-7007-11-78