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Chronic Alterations in Monoaminergic Cells in the Locus Coeruleus in Orexin Neuron-Ablated Narcoleptic Mice
Narcolepsy patients often suffer from insomnia in addition to excessive daytime sleepiness. Narcoleptic animals also show behavioral instability characterized by frequent transitions between all vigilance states, exhibiting very short bouts of NREM sleep as well as wakefulness. The instability of wa...
Autores principales: | Tsujino, Natsuko, Tsunematsu, Tomomi, Uchigashima, Motokazu, Konno, Kohtarou, Yamanaka, Akihiro, Kobayashi, Kazuto, Watanabe, Masahiko, Koyama, Yoshimasa, Sakurai, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726545/ https://www.ncbi.nlm.nih.gov/pubmed/23922890 http://dx.doi.org/10.1371/journal.pone.0070012 |
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