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Prognostic Significance of ESR1 Gene Amplification, mRNA/Protein Expression and Functional Profiles in High-Risk Early Breast Cancer: A Translational Study of the Hellenic Cooperative Oncology Group (HeCOG)

BACKGROUND: Discrepant data have been published on the incidence and prognostic significance of ESR1 gene amplification in early breast cancer. PATIENTS AND METHODS: Formalin-fixed paraffin-embedded tumor blocks were collected from women with early breast cancer participating in two HeCOG adjuvant t...

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Detalles Bibliográficos
Autores principales: Pentheroudakis, George, Kotoula, Vassiliki, Eleftheraki, Anastasia G., Tsolaki, Eleftheria, Wirtz, Ralph M., Kalogeras, Konstantine T., Batistatou, Anna, Bobos, Mattheos, Dimopoulos, Meletios A., Timotheadou, Eleni, Gogas, Helen, Christodoulou, Christos, Papadopoulou, Kyriaki, Efstratiou, Ioannis, Scopa, Chrisoula D., Papaspyrou, Irene, Vlachodimitropoulos, Dimitrios, Linardou, Helena, Samantas, Epaminontas, Pectasides, Dimitrios, Pavlidis, Nicholas, Fountzilas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726626/
https://www.ncbi.nlm.nih.gov/pubmed/23923010
http://dx.doi.org/10.1371/journal.pone.0070634