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High Content Screening as High Quality Assay for Biological Evaluation of Photosensitizers In Vitro

A novel single step assay approach to screen a library of photdynamic therapy (PDT) compounds was developed. Utilizing high content analysis (HCA) technologies several robust cellular parameters were identified, which can be used to determine the phototoxic effects of porphyrin compounds which have...

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Detalles Bibliográficos
Autores principales:	Vaz, Gisela M. F., Paszko, Edyta, Davies, Anthony M., Senge, Mathias O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726630/ https://www.ncbi.nlm.nih.gov/pubmed/23923014 http://dx.doi.org/10.1371/journal.pone.0070653

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