Common and Rare EGFR and KRAS Mutations in a Dutch Non-Small-Cell Lung Cancer Population and Their Clinical Outcome

INTRODUCTION: In randomly assigned studies with EGFR TKI only a minor proportion of patients with NSCLC have genetically profiled biopsies. Guidelines provide evidence to perform EGFR and KRAS mutation analysis in non-squamous NSCLC. We explored tumor biopsy quality offered for mutation testing, dif...

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Detalles Bibliográficos
Autores principales: Kerner, Gerald S. M. A., Schuuring, Ed, Sietsma, Johanna, Hiltermann, Thijo J. N., Pieterman, Remge M., de Leede, Gerard P. J., van Putten, John W. G., Liesker, Jeroen, Renkema, Tineke E. J., van Hengel, Peter, Platteel, Inge, Timens, Wim, Groen, Harry J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726644/
https://www.ncbi.nlm.nih.gov/pubmed/23922984
http://dx.doi.org/10.1371/journal.pone.0070346

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