Bioenergetics of the Calf Muscle in Friedreich Ataxia Patients Measured by 31P-MRS Before and After Treatment with Recombinant Human Erythropoietin

Friedreich ataxia (FRDA) is caused by a GAA repeat expansion in the FXN gene leading to reduced expression of the mitochondrial protein frataxin. Recombinant human erythropoietin (rhuEPO) is suggested to increase frataxin levels, alter mitochondrial function and improve clinical scores in FRDA patie...

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Detalles Bibliográficos
Autores principales: Nachbauer, Wolfgang, Boesch, Sylvia, Schneider, Rainer, Eigentler, Andreas, Wanschitz, Julia, Poewe, Werner, Schocke, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726701/
https://www.ncbi.nlm.nih.gov/pubmed/23922695
http://dx.doi.org/10.1371/journal.pone.0069229

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