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Tryptase Activation of Immortalized Human Urothelial Cell Mitogen-Activated Protein Kinase
The pathogenesis of interstitial cystitis/painful bladder syndrome (IC/PBS) is multifactorial, but likely involves urothelial cell dysfunction and mast cell accumulation in the bladder wall. Activated mast cells in the bladder wall release several inflammatory mediators, including histamine and tryp...
Autores principales: | Marentette, John O., Hauser, Paul J., Hurst, Robert E., Klumpp, David J., Rickard, Alice, McHowat, Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726738/ https://www.ncbi.nlm.nih.gov/pubmed/23922867 http://dx.doi.org/10.1371/journal.pone.0069948 |
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