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Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report

Monitoring intraocular pressure (IOP) is essential for pediatric cataract treatment but always difficult due to lack of cooperation in young children. We present the baseline characteristics and the first-year results of a long-term prospective cohort study, which are aimed to determine the relation...

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Autores principales: Lin, Haotian, Chen, Weirong, Luo, Lixia, Zhang, Xinyu, Chen, Jingjing, Lin, Zhuoling, Qu, Bo, Zhan, Jiao, Zheng, Danying, Zhong, Xiaojian, Tian, Zhen, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726742/
https://www.ncbi.nlm.nih.gov/pubmed/23922832
http://dx.doi.org/10.1371/journal.pone.0069867
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author Lin, Haotian
Chen, Weirong
Luo, Lixia
Zhang, Xinyu
Chen, Jingjing
Lin, Zhuoling
Qu, Bo
Zhan, Jiao
Zheng, Danying
Zhong, Xiaojian
Tian, Zhen
Liu, Yizhi
author_facet Lin, Haotian
Chen, Weirong
Luo, Lixia
Zhang, Xinyu
Chen, Jingjing
Lin, Zhuoling
Qu, Bo
Zhan, Jiao
Zheng, Danying
Zhong, Xiaojian
Tian, Zhen
Liu, Yizhi
author_sort Lin, Haotian
collection PubMed
description Monitoring intraocular pressure (IOP) is essential for pediatric cataract treatment but always difficult due to lack of cooperation in young children. We present the baseline characteristics and the first-year results of a long-term prospective cohort study, which are aimed to determine the relationship of the incidence of ocular hypertension (OH) in children after cataract surgery during the first-year period and the risk of developing late-onset glaucoma. Children were included with the following criteria: they were≤10 years old and scheduled to undergo cataract surgery with/without intraocular lens implantation; they were compliant with our follow-up protocol, which included monitoring IOP using a Tono-Pen under sedation or anesthesia. Incidence of OH, peak OH value, OH onset time and OH duration within a 12-month period following surgery were measured. In brief, 206 patients (379 eyes) were included and OH developed in 66 of 379 (17.4%) eyes. The mean follow-up period was 14.0±3.2 months (median, 12 months; range, 10–16 months). Moreover, 33 of 196 (16.8%) aphakic eyes and 33 of 183 (18.0%) IOL eyes were diagnosed with OH. The peak OH onset times were at 1-week (34/66, 51.5%) and 1-month (14/66, 21.2%) appointments postsurgery. The peak IOP value in the OH eyes was 29.9±7.5 mmHg (median, 29 mmHg; range, 21–48 mmHg). The duration of OH was 30.9±31.2 days (median, 30 days; range, 3–150 days). OH recurred in 13 eyes with a history of OH diagnosed within 1 month postsurgery (13/54, 24.1%), which needed temporary or long term use of antiglaucoma medications. In conclusion, the incidence of OH in children after cataract surgery was 17.4% during the first-year period. Children who have suffered elevated IOP in the first year after cataract surgery should be followed closely to determine if there is an increased risk of developing late-onset glaucoma.
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spelling pubmed-37267422013-08-06 Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report Lin, Haotian Chen, Weirong Luo, Lixia Zhang, Xinyu Chen, Jingjing Lin, Zhuoling Qu, Bo Zhan, Jiao Zheng, Danying Zhong, Xiaojian Tian, Zhen Liu, Yizhi PLoS One Research Article Monitoring intraocular pressure (IOP) is essential for pediatric cataract treatment but always difficult due to lack of cooperation in young children. We present the baseline characteristics and the first-year results of a long-term prospective cohort study, which are aimed to determine the relationship of the incidence of ocular hypertension (OH) in children after cataract surgery during the first-year period and the risk of developing late-onset glaucoma. Children were included with the following criteria: they were≤10 years old and scheduled to undergo cataract surgery with/without intraocular lens implantation; they were compliant with our follow-up protocol, which included monitoring IOP using a Tono-Pen under sedation or anesthesia. Incidence of OH, peak OH value, OH onset time and OH duration within a 12-month period following surgery were measured. In brief, 206 patients (379 eyes) were included and OH developed in 66 of 379 (17.4%) eyes. The mean follow-up period was 14.0±3.2 months (median, 12 months; range, 10–16 months). Moreover, 33 of 196 (16.8%) aphakic eyes and 33 of 183 (18.0%) IOL eyes were diagnosed with OH. The peak OH onset times were at 1-week (34/66, 51.5%) and 1-month (14/66, 21.2%) appointments postsurgery. The peak IOP value in the OH eyes was 29.9±7.5 mmHg (median, 29 mmHg; range, 21–48 mmHg). The duration of OH was 30.9±31.2 days (median, 30 days; range, 3–150 days). OH recurred in 13 eyes with a history of OH diagnosed within 1 month postsurgery (13/54, 24.1%), which needed temporary or long term use of antiglaucoma medications. In conclusion, the incidence of OH in children after cataract surgery was 17.4% during the first-year period. Children who have suffered elevated IOP in the first year after cataract surgery should be followed closely to determine if there is an increased risk of developing late-onset glaucoma. Public Library of Science 2013-07-29 /pmc/articles/PMC3726742/ /pubmed/23922832 http://dx.doi.org/10.1371/journal.pone.0069867 Text en © 2013 Lin et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Lin, Haotian
Chen, Weirong
Luo, Lixia
Zhang, Xinyu
Chen, Jingjing
Lin, Zhuoling
Qu, Bo
Zhan, Jiao
Zheng, Danying
Zhong, Xiaojian
Tian, Zhen
Liu, Yizhi
Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report
title Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report
title_full Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report
title_fullStr Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report
title_full_unstemmed Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report
title_short Ocular Hypertension after Pediatric Cataract Surgery: Baseline Characteristics and First-Year Report
title_sort ocular hypertension after pediatric cataract surgery: baseline characteristics and first-year report
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726742/
https://www.ncbi.nlm.nih.gov/pubmed/23922832
http://dx.doi.org/10.1371/journal.pone.0069867
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