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Effects of Sildenafil on the Gastrocnemius and Cardiac Muscles of Rats in a Model of Prolonged Moderate Exercise Training
Moderate exercise training improves energetic metabolism, tissue perfusion and induces cardiac and skeletal muscle remodeling. Sildenafil, a potent phosphodiesterase-5 inhibitor used to treat erectile dysfunction, reduces infarct size and increases tissue oxygenation in experimental models of cardio...
Autores principales: | Rinaldi, Barbara, Donniacuo, Maria, Sodano, Loredana, Gritti, Giulia, Signoriello, Simona, Parretta, Elisabetta, Berrino, Liberato, Urbanek, Konrad, Capuano, Annalisa, Rossi, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726744/ https://www.ncbi.nlm.nih.gov/pubmed/23922868 http://dx.doi.org/10.1371/journal.pone.0069954 |
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