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Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011
Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6%...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726754/ https://www.ncbi.nlm.nih.gov/pubmed/23922846 http://dx.doi.org/10.1371/journal.pone.0069895 |
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| author | Thoa, Le Phan Kim Chiang, Pai-Shan Khanh, Truong Huu Luo, Shu-Ting Dan, Tran Ngoc Hanh Wang, Ya-Fang Thuong, Tang Chi Chung, Wan-Yu Hung, Nguyen Thanh Wang, Jen-Ren Nhan, Le Nguyen Thanh Thinh, Le Quoc Su, Ih-Jen Dung, Than Duc Lee, Min-Shi |
| author_facet | Thoa, Le Phan Kim Chiang, Pai-Shan Khanh, Truong Huu Luo, Shu-Ting Dan, Tran Ngoc Hanh Wang, Ya-Fang Thuong, Tang Chi Chung, Wan-Yu Hung, Nguyen Thanh Wang, Jen-Ren Nhan, Le Nguyen Thanh Thinh, Le Quoc Su, Ih-Jen Dung, Than Duc Lee, Min-Shi |
| author_sort | Thoa, Le Phan Kim |
| collection | PubMed |
| description | Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam. |
| format | Online Article Text |
| id | pubmed-3726754 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | Public Library of Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-37267542013-08-06 Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011 Thoa, Le Phan Kim Chiang, Pai-Shan Khanh, Truong Huu Luo, Shu-Ting Dan, Tran Ngoc Hanh Wang, Ya-Fang Thuong, Tang Chi Chung, Wan-Yu Hung, Nguyen Thanh Wang, Jen-Ren Nhan, Le Nguyen Thanh Thinh, Le Quoc Su, Ih-Jen Dung, Than Duc Lee, Min-Shi PLoS One Research Article Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam. Public Library of Science 2013-07-29 /pmc/articles/PMC3726754/ /pubmed/23922846 http://dx.doi.org/10.1371/journal.pone.0069895 Text en © 2013 Thoa et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
| spellingShingle | Research Article Thoa, Le Phan Kim Chiang, Pai-Shan Khanh, Truong Huu Luo, Shu-Ting Dan, Tran Ngoc Hanh Wang, Ya-Fang Thuong, Tang Chi Chung, Wan-Yu Hung, Nguyen Thanh Wang, Jen-Ren Nhan, Le Nguyen Thanh Thinh, Le Quoc Su, Ih-Jen Dung, Than Duc Lee, Min-Shi Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011 |
| title | Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011 |
| title_full | Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011 |
| title_fullStr | Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011 |
| title_full_unstemmed | Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011 |
| title_short | Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011 |
| title_sort | genetic and antigenic characterization of enterovirus 71 in ho chi minh city, vietnam, 2011 |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726754/ https://www.ncbi.nlm.nih.gov/pubmed/23922846 http://dx.doi.org/10.1371/journal.pone.0069895 |
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