Cargando…

The Endoplasmic Reticulum-Resident Chaperone Heat Shock Protein 47 Protects the Golgi Apparatus from the Effects of O-Glycosylation Inhibition

The Golgi apparatus is important for the transport of secretory cargo. Glycosylation is a major post-translational event. Recognition of O-glycans on proteins is necessary for glycoprotein trafficking. In this study, specific inhibition of O-glycosylation (Golgi stress) induced the expression of end...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyata, Shingo, Mizuno, Tatsunori, Koyama, Yoshihisa, Katayama, Taiichi, Tohyama, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726774/
https://www.ncbi.nlm.nih.gov/pubmed/23922785
http://dx.doi.org/10.1371/journal.pone.0069732