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Hinged Plakin Domains Provide Specialized Degrees of Articulation in Envoplakin, Periplakin and Desmoplakin

Envoplakin, periplakin and desmoplakin are cytoskeletal proteins that provide structural integrity within the skin and heart by resisting shear forces. Here we reveal the nature of unique hinges within their plakin domains that provides divergent degrees of flexibility between rigid long and short a...

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Detalles Bibliográficos
Autores principales: Al-Jassar, Caezar, Bernadό, Pau, Chidgey, Martyn, Overduin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726778/
https://www.ncbi.nlm.nih.gov/pubmed/23922795
http://dx.doi.org/10.1371/journal.pone.0069767