A Case of Incidentally Discovered Subclinical Cushing Syndrome in a Patient with Chronic Fatigue and Anxiety

Subclinical Cushing syndrome (SCS) is a hypothalamic-pituitary-adrenal axis abnormality characterized by autonomous cortisol secretion in patients with no typical signs or symptoms of Cushing syndrome. SCS patients may have adverse metabolic and cardiovascular effects due to slight, but continuous g...

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Detalles Bibliográficos
Autores principales: Nam, Kyung-Jee, Kim, Yun-Jin, Lee, Sang-Yeoup, Lee, Jeong-Gyu, Cho, Young-Hye, Lee, Yu-Hyun, Choi, Eun-Jung, Tak, Young-Jin, Yi, Dong-Won, Park, Sung-Woo, Jeong, Dong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Family Medicine 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726797/
https://www.ncbi.nlm.nih.gov/pubmed/23904959
http://dx.doi.org/10.4082/kjfm.2013.34.4.289
Descripción
Sumario:Subclinical Cushing syndrome (SCS) is a hypothalamic-pituitary-adrenal axis abnormality characterized by autonomous cortisol secretion in patients with no typical signs or symptoms of Cushing syndrome. SCS patients may have adverse metabolic and cardiovascular effects due to slight, but continuous glucocorticoid secretion. Glucocorticoids also affect behavior, mood, neural activity, and a number of specific biochemical processes in the central nervous system. Here, we report a case of SCS due to an adrenal incidentaloma in a hypertensive diabetic patient who presented with chronic fatigue and anxiety that disappeared after the removal of the adrenal adenoma.

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