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Nucleic acids and endosomal pattern recognition: how to tell friend from foe?

The innate immune system has evolved endosomal and cytoplasmic receptors for the detection of viral nucleic acids as sensors for virus infection. Some of these pattern recognition receptors (PRR) detect features of viral nucleic acids that are not found in the host such as long stretches of double-s...

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Detalles Bibliográficos
Autores principales: Brencicova, Eva, Diebold, Sandra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726833/
https://www.ncbi.nlm.nih.gov/pubmed/23908972
http://dx.doi.org/10.3389/fcimb.2013.00037