308-nm Excimer Lamp for the Treatment of Alopecia Areata: Clinical Trial on 16 Cases

BACKGROUND: Alopecia areata (AA) is considered as a T-cell mediated autoimmune disorder. The 308-nm excimer laser is thought to be capable of inducing T-cell apoptosis in vitro, suggesting that the 308-nm excimer lamp (not laser) might be effective for the treatment of AA. We examined the effectiven...

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Detalles Bibliográficos
Autores principales: Ohtsuki, Akiko, Hasegawa, Toshio, Komiyama, Etsuko, Takagi, Atsushi, Kawasaki, Junko, Ikeda, Shigaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
E-Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726899/
https://www.ncbi.nlm.nih.gov/pubmed/23919022
http://dx.doi.org/10.4103/0019-5154.113954
Descripción
Sumario:BACKGROUND: Alopecia areata (AA) is considered as a T-cell mediated autoimmune disorder. The 308-nm excimer laser is thought to be capable of inducing T-cell apoptosis in vitro, suggesting that the 308-nm excimer lamp (not laser) might be effective for the treatment of AA. We examined the effectiveness of the 308-nm excimer lamp for treating AA. MATERIALS AND METHODS: We treated 16 patients with single AA and multiple AA (MAA). The lesions were irradiated with a 308-nm excimer lamp at 2-week intervals. RESULTS: Hair regrowth was observed in 14 patients. Among them, 10 patients showed more than 50% hair re-growth. Our results suggested that the 308-nm excimer lamp system is effective and safe for the treatment of single AA and MAA. CONCLUSION: Our results suggest that the 308-nm excimer lamp is a good therapeutic alternative without serious side effect for treating AA.

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