Cargando…

Analysis, Isolation, and Activation of Antigen-Specific CD4(+) and CD8(+) T Cells by Soluble MHC-Peptide Complexes

T cells constitute the core of adaptive cellular immunity and protect higher organisms against pathogen infections and cancer. Monitoring of disease progression as well as prophylactic or therapeutic vaccines and immunotherapies call for conclusive detection, analysis, and sorting of antigen-specifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmidt, Julien, Dojcinovic, Danijel, Guillaume, Philippe, Luescher, Immanuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726995/ https://www.ncbi.nlm.nih.gov/pubmed/23908656 http://dx.doi.org/10.3389/fimmu.2013.00218

Ejemplares similares

Identification and isolation of high avidity tumor-specific CD8 T cells by experimentally assessing pMHC-TCR binding parameters with soluble pMHC complexes
por: Schmidt, Julien, et al.
Publicado: (2015)

CD8 T cell function and cross-reactivity explored by stepwise increased peptide-HLA versus TCR affinity
por: Baumgaertner, Petra, et al.
Publicado: (2022)

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8(+) T cell dysfunction in melanoma patients
por: Fourcade, Julien, et al.
Publicado: (2010)

CD8(+) T-cell cross-competition is governed by peptide–MHC class I stability
por: Galea, Ian, et al.
Publicado: (2012)

NY-ESO-1-Specific Circulating CD4(+) T Cells in Ovarian Cancer Patients Are Prevalently T(H)1 Type Cells Undetectable in the CD25(+)FOXP3(+)Treg Compartment
por: Redjimi, Nassima, et al.
Publicado: (2011)

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding
por: Renard, Valery, et al.
Publicado: (1996)

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes
por: Kessler, Benedikt, et al.
Publicado: (1997)

CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56(lck) Complexes
por: Arcaro, Alexandre, et al.
Publicado: (2001)

High Peptide Dose Vaccination Promotes the Early Selection of Tumor Antigen-Specific CD8 T-Cells of Enhanced Functional Competence
por: Carretero-Iglesia, Laura, et al.
Publicado: (2020)

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
por: James, Eddie A., et al.
Publicado: (2009)

The Combination of CD8αα and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken γδT Cells Response
por: Liu, Yanjie, et al.
Publicado: (2020)

An Unusual MHC Molecule Generates Protective CD8+ T Cell Responses to Chronic Infection
por: Tsitsiklis, Alexandra, et al.
Publicado: (2020)

Subretinal Injection of HY Peptides Induces Systemic Antigen-Specific Inhibition of Effector CD4(+) and CD8(+) T-Cell Responses
por: Vendomèle, Julie, et al.
Publicado: (2018)

Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8(+) T Cell Tolerance Development
por: Damo, Martina, et al.
Publicado: (2021)

A Novel HLA-B18 Restricted CD8+ T Cell Epitope Is Efficiently Cross-Presented by Dendritic Cells from Soluble Tumor Antigen
por: Zhao, Rona Y., et al.
Publicado: (2012)

Enhanced Detection of Antigen-Specific CD4(+) T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers
por: Holland, Christopher J., et al.
Publicado: (2015)

Induction of broad multifunctional CD8+ and CD4+ T cells by hepatitis B virus antigen-based synthetic long peptides ex vivo
por: Jansen, Diahann T. S. L., et al.
Publicado: (2023)

MHC-based detection of antigen-specific CD8(+) T cell responses
por: Hadrup, Sine Reker, et al.
Publicado: (2010)

Conformation-selective rather than avidity-based binding to tumor associated antigen derived peptide-MHC enables targeting of WT1-pMHC low expressing cancer cells by anti-WT1-pMHC/CD3 T cell engagers
por: Walseng, Even, et al.
Publicado: (2023)

DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease
por: Lambert, Laura, et al.
Publicado: (2016)

Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus
por: Van Laethem, François, et al.
Publicado: (2020)

The TCR’s sensitivity to self-peptide–MHC dictates the ability of naïve CD8(+) T cells to respond to foreign antigens
por: Fulton, Ross B., et al.
Publicado: (2014)

Non-Stimulatory pMHC Enhance CD8 T Cell Effector Functions by Recruiting Coreceptor-Bound Lck
por: Zhao, Xiang, et al.
Publicado: (2021)

Staining of activated ß(2)-integrins in combination with CD137 and CD154 for sensitive identification of functional antigen-specific CD4(+) and CD8(+) T cells
por: Schöllhorn, Anna, et al.
Publicado: (2023)

Re-Directing CD4(+) T Cell Responses with the Flanking Residues of MHC Class II-Bound Peptides: The Core is Not Enough
por: Holland, Christopher J., et al.
Publicado: (2013)

Delivery of Antigen to CD8(+) Dendritic Cells by Fusing Antigen With Formyl Peptide Receptor-Like 1 Inhibitor Protein Induces Antitumor Immunity
por: Chiang, Chen-Yi, et al.
Publicado: (2019)

MHC-Optimized Peptide Scaffold for Improved Antigen Presentation and Anti-Tumor Response
por: Tagliamonte, Maria, et al.
Publicado: (2021)

Regulation of MHC Class II-Peptide Complex Expression by Ubiquitination
por: Cho, Kyung-Jin, et al.
Publicado: (2013)

Proofreading of Peptide—MHC Complexes through Dynamic Multivalent Interactions
por: Thomas, Christoph, et al.
Publicado: (2017)

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation
por: Wieczorek, Marek, et al.
Publicado: (2017)

Pulmonary Delivery of Virosome-Bound Antigen Enhances Antigen-Specific CD4(+) T Cell Proliferation Compared to Liposome-Bound or Soluble Antigen
por: Blom, Rebecca A. M., et al.
Publicado: (2017)

Targeting 4-1BB (CD137) to enhance CD8 T cell responses with poxviruses and viral antigens
por: Zhao, Yuan, et al.
Publicado: (2012)

Human Macrophages Escape Inhibition of Major Histocompatibility Complex-Dependent Antigen Presentation by Cytomegalovirus and Drive Proliferation and Activation of Memory CD4(+) and CD8(+) T Cells
por: Frascaroli, Giada, et al.
Publicado: (2018)

Cooperative binding of T cell receptor and CD4 to peptide-MHC enhances antigen sensitivity
por: Rushdi, Muaz Nik, et al.
Publicado: (2022)

Optimized Peptide–MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells
por: Dolton, Garry, et al.
Publicado: (2018)

Impact of peptide:HLA complex stability for the identification of SARS-CoV-2-specific CD8(+)T cells
por: Lie-Andersen, Olivia, et al.
Publicado: (2023)

CpG Oligodeoxinucleotides and Flagellin Modulate the Immune Response to Antigens Targeted to CD8α(+) and CD8α(−) Conventional Dendritic Cell Subsets
por: Antonialli, Renan, et al.
Publicado: (2017)

Cognate Antigen Stimulation Generates Potent CD8(+) Inflammatory Effector T Cells
por: Sung, Hsueh-Cheng, et al.
Publicado: (2013)

Priming of CD8(+) T Cell Responses to Liver Stage Malaria Parasite Antigens
por: Corradin, Giampietro, et al.
Publicado: (2014)

Antigen Processing by Macroautophagy for MHC Presentation
por: Münz, Christian
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_6ldbaalqru6v8e3qmrt0mqei80