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Compartment Model Predicts VEGF Secretion and Investigates the Effects of VEGF Trap in Tumor-Bearing Mice

Angiogenesis, the formation of new blood vessels from existing vasculature, is important in tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth factor (VEGF), which has been targeted in numerous anti-angiogenic therapies aimed at inhibiting tumor angiogenesis....

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Detalles Bibliográficos
Autores principales:	Finley, Stacey D., Dhar, Manjima, Popel, Aleksander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727077/ https://www.ncbi.nlm.nih.gov/pubmed/23908970 http://dx.doi.org/10.3389/fonc.2013.00196

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