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Elucidation of Novel Structural Scaffold in Rohu TLR2 and Its Binding Site Analysis with Peptidoglycan, Lipoteichoic Acid and Zymosan Ligands, and Downstream MyD88 Adaptor Protein

Toll-like receptors (TLRs) play key roles in sensing wide array of microbial signatures and induction of innate immunity. TLR2 in fish resembles higher eukaryotes by sensing peptidoglycan (PGN) and lipoteichoic acid (LTA) of bacterial cell wall and zymosan of yeasts. However, in fish TLR2, no study...

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Detalles Bibliográficos
Autores principales:	Sahoo, Bikash Ranjan, Basu, Madhubanti, Swain, Banikalyan, Dikhit, Manas Ranjan, Jayasankar, Pallipuram, Samanta, Mrinal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727187/ https://www.ncbi.nlm.nih.gov/pubmed/23956969 http://dx.doi.org/10.1155/2013/185282

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