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Mechanism of calsequestrin regulation of single cardiac ryanodine receptor in normal and pathological conditions

Release of Ca(2+) from the sarcoplasmic reticulum (SR) drives contractile function of cardiac myocytes. Luminal Ca(2+) regulation of SR Ca(2+) release is fundamental not only in physiology but also in physiopathology because abnormal luminal Ca(2+) regulation is known to lead to arrhythmias, catecho...

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Detalles Bibliográficos
Autores principales:	Chen, Haiyan, Valle, Giorgia, Furlan, Sandra, Nani, Alma, Gyorke, Sandor, Fill, Michael, Volpe, Pompeo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727306/ https://www.ncbi.nlm.nih.gov/pubmed/23858002 http://dx.doi.org/10.1085/jgp.201311022

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