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Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45
Insulin stimulates glucose transport in fat and muscle cells by regulating delivery of the facilitative glucose transporter, glucose transporter isoform 4 (GLUT4), to the plasma membrane. In the absence of insulin, GLUT4 is sequestered away from the general recycling endosomal pathway into specializ...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727931/ https://www.ncbi.nlm.nih.gov/pubmed/23741049 http://dx.doi.org/10.1091/mbc.E13-01-0011 |