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Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis

Nesprin-3 is a nuclear envelope protein that connects the nucleus to intermediate filaments by interacting with plectin. To investigate the role of nesprin-3 in the perinuclear localization of plectin, we generated nesprin-3–knockout mice and examined the effects of nesprin-3 deficiency in different...

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Detalles Bibliográficos
Autores principales: Ketema, Mirjam, Kreft, Maaike, Secades, Pablo, Janssen, Hans, Sonnenberg, Arnoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727937/
https://www.ncbi.nlm.nih.gov/pubmed/23761073
http://dx.doi.org/10.1091/mbc.E13-02-0100