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A hexadecylamide derivative of hyaluronan (HYMOVIS®) has superior beneficial effects on human osteoarthritic chondrocytes and synoviocytes than unmodified hyaluronan
BACKGROUND: Intra-articular hyaluronan (HA) injection provides symptomatic benefit in the treatment of osteoarthritis (OA). Previously we found superior beneficial effects in a large animal OA model of a hexadecylamide derivative compared with unmodified HA of the same initial molecular weight. The...
Autores principales: | Smith, Margaret M, Russell, Amy K, Schiavinato, Antonella, Little, Christopher B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727958/ https://www.ncbi.nlm.nih.gov/pubmed/23889808 http://dx.doi.org/10.1186/1476-9255-10-26 |
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