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Functional characterisation of human cells harbouring a novel t(2p;7p) translocation involving TNS3 and EXOC6B genes
BACKGROUND: Tensin3 is an intracellular cytoskeleton-regulating protein, the loss of which is associated with increased cell motility, as has been observed in some human cancers. A novel chromosomal translocation, t(2;7)(p13;p12), present in a patient with a complex syndromic phenotype, directly inv...
Autores principales: | Ludwig, Desiree, Carter, Jessica, Smith, James R, Borsani, Giuseppe, Barlati, Sergio, Hafizi, Sassan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728010/ https://www.ncbi.nlm.nih.gov/pubmed/23809228 http://dx.doi.org/10.1186/1471-2350-14-65 |
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