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Tolerability and safety of artesunate-amodiaquine and artemether-lumefantrine fixed dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria: two open-label, randomized trials in Nimba County, Liberia
BACKGROUND: Safety surveillance of widely used artemisinin-based combination therapy (ACT) is essential, but tolerability data in the over five years age group are largely anecdotal. METHODS: Two open-label, randomized trials were conducted in Nimba County, Liberia: i) the main tolerability trial wi...
Autores principales: | Schramm, Birgit, Valeh, Parastou, Baudin, Elisabeth, Mazinda, Charles S, Smith, Richard, Pinoges, Loretxu, Sundaygar, Timothy, Zolia, Yah M, Jones, Joel J, Comte, Eric, Bruneel, Arnaud, Branger, Michel, Jullien, Vincent, Carn, Gwenaelle, Kiechel, Jean-René, Ashley, Elizabeth A, Guérin, Philippe J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728046/ https://www.ncbi.nlm.nih.gov/pubmed/23866736 http://dx.doi.org/10.1186/1475-2875-12-250 |
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