Cargando…

Luminescent multiplex viability assay for Trypanosoma brucei gambiense

BACKGROUND: New compounds for the treatment of human African trypanosomiasis (HAT) are urgently required. Trypanosoma brucei (T.b.) gambiense is the leading cause of HAT, yet T.b. gambiense is often not the prime target organism in drug discovery. This may be attributed to the difficulties in handli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Van Reet, Nick, Pyana, Pati, Rogé, Stijn, Claes, Filip, Büscher, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728213/ https://www.ncbi.nlm.nih.gov/pubmed/23856321 http://dx.doi.org/10.1186/1756-3305-6-207

Ejemplares similares

Isolation of Trypanosoma brucei gambiense from Cured and Relapsed Sleeping Sickness Patients and Adaptation to Laboratory Mice
por: Pyana, Patient Pati, et al.
Publicado: (2011)

Melarsoprol Sensitivity Profile of Trypanosoma brucei gambiense Isolates from Cured and Relapsed Sleeping Sickness Patients from the Democratic Republic of the Congo
por: Pyana Pati, Patient, et al.
Publicado: (2014)

Identification of Peptide Mimotopes of Trypanosoma brucei gambiense Variant Surface Glycoproteins
por: Van Nieuwenhove, Liesbeth Carolien, et al.
Publicado: (2011)

Expression of Trypanosoma brucei gambiense Antigens in Leishmania tarentolae. Potential for Use in Rapid Serodiagnostic Tests (RDTs)
por: Rooney, Barrie, et al.
Publicado: (2015)

Single nucleotide polymorphisms and copy-number variations in the Trypanosoma brucei repeat (TBR) sequence can be used to enhance amplification and genotyping of Trypanozoon strains
por: Van Reet, Nick, et al.
Publicado: (2021)

Recombinant Antigens Expressed in Pichia pastoris for the Diagnosis of Sleeping Sickness Caused by Trypanosoma brucei gambiense
por: Rogé, Stijn, et al.
Publicado: (2014)

Target product profile: diagnostic test for Trypanosoma brucei gambiense
por: Priotto, Gerardo, et al.
Publicado: (2023)

Deep kinetoplast genome analyses result in a novel molecular assay for detecting Trypanosoma brucei gambiense-specific minicircles
por: Geerts, Manon, et al.
Publicado: (2022)

Aquaporin 2 Mutations in Trypanosoma brucei gambiense Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
por: Graf, Fabrice E., et al.
Publicado: (2013)

Target product profile: Trypanosoma brucei gambiense test to verify elimination
por: Priotto, Gerardo, et al.
Publicado: (2023)

Target product profile: Trypanosoma brucei gambiense test for low-prevalence settings
por: Priotto, Gerardo, et al.
Publicado: (2023)

A Panel of Trypanosoma brucei Strains Tagged with Blue and Red-Shifted Luciferases for Bioluminescent Imaging in Murine Infection Models
por: Van Reet, Nick, et al.
Publicado: (2014)

Trypanosoma brucei gambiense-iELISA: A Promising New Test for the Post-Elimination Monitoring of Human African Trypanosomiasis
por: Geerts, Manon, et al.
Publicado: (2020)

Untreated Human Infections by Trypanosoma brucei gambiense Are Not 100% Fatal
por: Jamonneau, Vincent, et al.
Publicado: (2012)

Two-Year Follow-Up of Trypanosoma brucei gambiense Serology after Successful Treatment of Human African Trypanosomiasis: Results of Four Different Sero-Diagnostic Tests
por: Inocencio da Luz, Raquel, et al.
Publicado: (2022)

Specificity of malaria rapid diagnostic tests is affected by Trypanosoma brucei gambiense sleeping sickness
por: Gillet, Philippe, et al.
Publicado: (2012)

Murine Models for Trypanosoma brucei gambiense Disease Progression—From Silent to Chronic Infections and Early Brain Tropism
por: Giroud, Christiane, et al.
Publicado: (2009)

Correction: Murine Models for Trypanosoma brucei gambiense Disease Progression—From Silent to Chronic Infections and Early Brain Tropism
por: Giroud, Christiane, et al.
Publicado: (2016)

Identification of Trypanosoma brucei gambiense in naturally infected dogs in Nigeria
por: Umeakuana, Paschal Ugochukwu, et al.
Publicado: (2019)

Diagnostic Accuracy of Loopamp Trypanosoma brucei Detection Kit for Diagnosis of Human African Trypanosomiasis in Clinical Samples
por: Mitashi, Patrick, et al.
Publicado: (2013)

Identification of Mimotopes with Diagnostic Potential for Trypanosoma brucei gambiense Variant Surface Glycoproteins Using Human Antibody Fractions
por: Van Nieuwenhove, Liesbeth, et al.
Publicado: (2012)

Cerebrospinal Fluid Neopterin as Marker of the Meningo-Encephalitic Stage of Trypanosoma brucei gambiense Sleeping Sickness
por: Tiberti, Natalia, et al.
Publicado: (2012)

Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections
por: Bucheton, B, et al.
Publicado: (2011)

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense
por: Cooper, Anneli, et al.
Publicado: (2016)

Neural Damage in Experimental Trypanosoma brucei gambiense Infection: The Suprachiasmatic Nucleus
por: Tesoriero, Chiara, et al.
Publicado: (2018)

Bioluminescent Imaging of Trypanosoma brucei Shows Preferential Testis Dissemination Which May Hamper Drug Efficacy in Sleeping Sickness
por: Claes, Filip, et al.
Publicado: (2009)

The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
por: Capewell, Paul, et al.
Publicado: (2013)

Diagnostic Accuracy of PCR in gambiense Sleeping Sickness Diagnosis, Staging and Post-Treatment Follow-Up: A 2-year Longitudinal Study
por: Deborggraeve, Stijn, et al.
Publicado: (2011)

The Genome Sequence of Trypanosoma brucei gambiense, Causative Agent of Chronic Human African Trypanosomiasis
por: Jackson, Andrew P., et al.
Publicado: (2010)

The elimination of Trypanosoma brucei gambiense? Challenges of reservoir hosts and transmission cycles: Expect the unexpected
por: Mehlitz, D., et al.
Publicado: (2019)

Neopterin Is a Cerebrospinal Fluid Marker for Treatment Outcome Evaluation in Patients Affected by Trypanosoma brucei gambiense Sleeping Sickness
por: Tiberti, Natalia, et al.
Publicado: (2013)

NECT Is Next: Implementing the New Drug Combination Therapy for Trypanosoma brucei gambiense Sleeping Sickness
por: Yun, Oliver, et al.
Publicado: (2010)

Trypanosoma brucei gambiense Adaptation to Different Mammalian Sera Is Associated with VSG Expression Site Plasticity
por: Cordon-Obras, Carlos, et al.
Publicado: (2013)

Trypanosoma brucei gambiense Infections in Mice Lead to Tropism to the Reproductive Organs, and Horizontal and Vertical Transmission
por: Biteau, Nicolas, et al.
Publicado: (2016)

Midgut expression of immune-related genes in Glossina palpalis gambiensis challenged with Trypanosoma brucei gambiense
por: Hamidou Soumana, Illiassou, et al.
Publicado: (2014)

Unusual MRI Findings in African Trypanosoma brucei gambiense Trypanosomiasis: Dentate Nuclei and Hypothalamic Lesions
por: Boukobza, Monique, et al.
Publicado: (2020)

Immunoinformatic design of a putative multi-epitope vaccine candidate against Trypanosoma brucei gambiense
por: Danazumi, Ammar Usman, et al.
Publicado: (2022)

Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of Trypanosoma brucei gambiense Infection: A Multi-centric Prospective Study
por: Bisser, Sylvie, et al.
Publicado: (2016)

Trypanosome SL-RNA detection in blood and cerebrospinal fluid to demonstrate active gambiense human African trypanosomiasis infection
por: Ngay Lukusa, Ipos, et al.
Publicado: (2021)

Target product profile: diagnostic test for Trypanosoma brucei rhodesiense
por: Priotto, Gerardo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_du4ln4jcbl4retvj6mq5jsrm40