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Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis

Bacterial pathogens like Mycobacterium tuberculosis (Mtb) encounter acidic microenvironments in the host and must maintain their acid-base homeostasis to survive. A genetic screen identified two Mtb strains that cannot control intrabacterial pH (pH(IB)) in an acidic environment; infection with eithe...

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Detalles Bibliográficos
Autores principales:	Darby, Crystal M., Ingólfsson, Helgi I., Jiang, Xiuju, Shen, Chun, Sun, Mingna, Zhao, Nan, Burns, Kristin, Liu, Gang, Ehrt, Sabine, Warren, J. David, Anderson, Olaf S., Brickner, Steven J., Nathan, Carl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728290/ https://www.ncbi.nlm.nih.gov/pubmed/23935911 http://dx.doi.org/10.1371/journal.pone.0068942

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