Leprosy Association with Low MASP-2 Levels Generated by MASP2 Haplotypes and Polymorphisms Flanking MAp19 Exon 5

BACKGROUND: The gene MASP2 (mannan-binding lectin (MBL)-associated serine protease 2) encodes two proteins, MASP-2 and MAp19 (MBL-associated protein of 19 kDa), bound in plasma to MBL and ficolins. The binding of MBL/MASP-2 and ficolin/MASP-2 complexes to microorganisms activates the lectin pathway...

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Detalles Bibliográficos
Autores principales: Boldt, Angelica Beate Winter, Goeldner, Isabela, Stahlke, Ewalda R. S., Thiel, Steffen, Jensenius, Jens Christian, de Messias-Reason, Iara José Taborda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728295/
https://www.ncbi.nlm.nih.gov/pubmed/23935922
http://dx.doi.org/10.1371/journal.pone.0069054

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