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Upregulation of TrkB Promotes Epithelial-Mesenchymal Transition and Anoikis Resistance in Endometrial Carcinoma

Mechanisms governing the metastasis of endometrial carcinoma (EC) are poorly defined. Recent data support a role for the cell surface receptor tyrosine kinase TrkB in the progression of several human tumors. Here we present evidence for a direct role of TrkB in human EC. Immunohistochemical analysis...

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Detalles Bibliográficos
Autores principales: Bao, Wei, Qiu, Haifeng, Yang, Tingting, Luo, Xin, Zhang, Huijuan, Wan, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728299/
https://www.ncbi.nlm.nih.gov/pubmed/23936232
http://dx.doi.org/10.1371/journal.pone.0070616