Cargando…

Fractalkine Depresses Cardiomyocyte Contractility

BACKGROUND: Our laboratory reported that male mice with cardiomyocyte-selective knockout of the prostaglandin E(2) EP4 receptor sub-type (EP4 KO) exhibit reduced cardiac function. Gene array on left ventricles (LV) showed increased fractalkine, a chemokine implicated in heart failure. We therefore h...

Descripción completa

Detalles Bibliográficos
Autores principales: Taube, David, Xu, Jiang, Yang, Xiao-Ping, Undrovinas, Albertas, Peterson, Edward, Harding, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728327/
https://www.ncbi.nlm.nih.gov/pubmed/23936109
http://dx.doi.org/10.1371/journal.pone.0069832