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Fractalkine Depresses Cardiomyocyte Contractility
BACKGROUND: Our laboratory reported that male mice with cardiomyocyte-selective knockout of the prostaglandin E(2) EP4 receptor sub-type (EP4 KO) exhibit reduced cardiac function. Gene array on left ventricles (LV) showed increased fractalkine, a chemokine implicated in heart failure. We therefore h...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728327/ https://www.ncbi.nlm.nih.gov/pubmed/23936109 http://dx.doi.org/10.1371/journal.pone.0069832 |