Cargando…

Development of an Epidermal Growth Factor Derivative with EGFR Blocking Activity

The members of the epidermal growth factor (EGF)/ErbB family are prime targets for cancer therapy. However, the therapeutic efficiency of the existing anti-ErbB agents is limited. Thus, identifying new molecules that inactivate the ErbB receptors through novel strategies is an important goal on canc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Panosa, Clara, Tebar, Francesc, Ferrer-Batallé, Montserrat, Fonge, Humphrey, Seno, Masaharu, Reilly, Raymond M., Massaguer, Anna, De Llorens, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728333/ https://www.ncbi.nlm.nih.gov/pubmed/23935985 http://dx.doi.org/10.1371/journal.pone.0069325

Ejemplares similares

Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates
por: Tikum, Anjong Florence, et al.
Publicado: (2022)

Near infrared imaging of epidermal growth factor receptor positive xenografts in mice with domain I/II specific antibody fragments
por: Bernhard, Wendy, et al.
Publicado: (2019)

Identification of Caveolin-1 as a Potential Causative Factor in the Generation of Trastuzumab Resistance in Breast Cancer Cells
por: Sekhar, Sreeja C, et al.
Publicado: (2013)

Estrone-3-Sulphate, a Potential Novel Ligand for Targeting Breast Cancers
por: Banerjee, Nilasha, et al.
Publicado: (2013)

Comparative Study of Blood-Based Biomarkers, α2,3-Sialic Acid PSA and PHI, for High-Risk Prostate Cancer Detection
por: Ferrer-Batallé, Montserrat, et al.
Publicado: (2017)

(89)Zr-nimotuzumab for immunoPET imaging of epidermal growth factor receptor I
por: Chekol, Rufael, et al.
Publicado: (2018)

Evaluation of nimotuzumab Fab(2) as an optical imaging agent in EGFR positive cancers
por: Bernhard, Wendy, et al.
Publicado: (2023)

Near infrared fluorescence imaging of EGFR expression in vivo using IRDye800CW-nimotuzumab
por: Bernhard, Wendy, et al.
Publicado: (2017)

Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas
por: Magkou, Christina, et al.
Publicado: (2008)

(89)Zr-Labeled Domain II-Specific scFv-Fc ImmunoPET Probe for Imaging Epidermal Growth Factor Receptor In Vivo
por: Alizadeh, Elahe, et al.
Publicado: (2021)

Characterisation of the main PSA glycoforms in aggressive prostate cancer
por: Gratacós-Mulleras, Anna, et al.
Publicado: (2020)

Therapeutic potential of nimotuzumab PEGylated-maytansine antibody drug conjugates against EGFR positive xenograft
por: Hartimath, Siddesh V., et al.
Publicado: (2019)

Butein Inhibited In Vitro Hexokinase-2-Mediated Tumor Glycolysis in Hepatocellular Carcinoma by Blocking Epidermal Growth Factor Receptor (EGFR)
por: Liao, Weirong, et al.
Publicado: (2018)

Influence of Macrocyclization on Allosteric, Juxtamembrane-Derived, Stapled Peptide Inhibitors of the Epidermal Growth Factor Receptor (EGFR)
por: Sinclair, Julie K.-L., et al.
Publicado: (2014)

Epidermal growth factor receptors (EGFR) in human ovarian cancer.
por: Owens, O. J., et al.
Publicado: (1991)

Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer
por: Berasain, Carmen, et al.
Publicado: (2011)

Nuclear localization of epidermal growth factor receptor (EGFR) in ameloblastomas
por: Pereira, Núbia Braga, et al.
Publicado: (2015)

Cyclic Guanosine Monophosphate (cGMP)-Dependent Protein Kinase II Blocks Epidermal Growth Factor (EGF)/Epidermal Growth Factor Receptor (EGFR)-Induced Biological Effects on Osteosarcoma Cells
por: Li, Dapeng, et al.
Publicado: (2018)

Nimotuzumab Site-Specifically Labeled with (89)Zr and (225)Ac Using SpyTag/SpyCatcher for PET Imaging and Alpha Particle Radioimmunotherapy of Epidermal Growth Factor Receptor Positive Cancers
por: Solomon, Viswas Raja, et al.
Publicado: (2020)

AXL/epidermal growth factor receptor (EGFR) complexes in breast cancer - culprits for resistance to EGFR inhibitors?
por: Heideman, Marinus R, et al.
Publicado: (2013)

Improvement of Prostate Cancer Diagnosis by Detecting PSA Glycosylation-Specific Changes: Erratum
por: Llop, Esther, et al.
Publicado: (2018)

Improvement of Prostate Cancer Diagnosis by Detecting PSA Glycosylation-Specific Changes
por: Llop, Esther, et al.
Publicado: (2016)

Assessment of Epidermal Growth Factor Receptor (EGFR) expression in human meningioma
por: Wernicke, A Gabriella, et al.
Publicado: (2010)

Targeting Epidermal Growth Factor Receptor (EGFR) in Pediatric Colorectal Cancer
por: De Pasquale, Maria Debora, et al.
Publicado: (2020)

Association of epidermal growth factor receptor (EGFR) gene polymorphisms with endometriosis
por: Wang, Yu-Mei, et al.
Publicado: (2019)

Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Global Metabolic Pathways in EGFR-mutated Lung Adenocarcinoma
por: Makinoshima, Hideki, et al.
Publicado: (2014)

Integrating nanoparticle quantification and statistical design of experiments for efficient HIV-1 virus-like particle production in High Five cells
por: Puente-Massaguer, Eduard, et al.
Publicado: (2020)

Metastasis Model of Cancer Stem Cell-Derived Tumors
por: Mansour, Hager, et al.
Publicado: (2020)

Production and Semi-Automated Processing of (89)Zr Using a Commercially Available TRASIS MiniAiO Module
por: Gaja, Vijay, et al.
Publicado: (2020)

Hypermethylated Epidermal growth factor receptor (EGFR) promoter is associated with gastric cancer
por: Weng, Xiaoling, et al.
Publicado: (2015)

Immune Responses to Epidermal Growth Factor Receptor (EGFR) and Their Application for Cancer Treatment
por: Sasada, Tetsuro, et al.
Publicado: (2016)

Piperonylic acid stimulates keratinocyte growth and survival by activating epidermal growth factor receptor (EGFR)
por: Lee, Dohyun, et al.
Publicado: (2018)

Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer
por: Peraldo-Neia, Caterina, et al.
Publicado: (2011)

Quantification of epidermal growth factor receptor (EGFR) mutation may be a predictor of EGFR‐tyrosine kinase inhibitor treatment response
por: Park, Ha Young, et al.
Publicado: (2016)

Epidermal growth factor receptor (EGFR) mutations in lung cancer: preclinical and clinical data
por: Jorge, S.E.D.C., et al.
Publicado: (2014)

Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage
por: Rayego-Mateos, Sandra, et al.
Publicado: (2018)

Toward structure-based drug design against the epidermal growth factor receptor (EGFR)
por: Haddad, Yazan, et al.
Publicado: (2020)

Prognostic Worth of Epidermal Growth Factor Receptor (EGFR) in Patients with Head and Neck Tumors
por: Barnes, Precious, et al.
Publicado: (2020)

Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma
por: Pala, Andrej, et al.
Publicado: (2012)

Structure-Based Drug Design Studies Toward the Discovery of Novel Chalcone Derivatives as Potential Epidermal Growth Factor Receptor (EGFR) Inhibitors
por: Al-Anazi, Menier, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6meah9bt5347emk520esubgdvv