The Q175 Mouse Model of Huntington’s Disease Shows Gene Dosage- and Age-Related Decline in Circadian Rhythms of Activity and Sleep

Sleep and circadian disruptions are commonly reported by patients with neurodegenerative diseases, suggesting these may be an endophenotype of the disorders. Several mouse models of Huntington’s disease (HD) that recapitulate the disease progression and motor dysfunction of HD also exhibit sleep and...

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Detalles Bibliográficos
Autores principales: Loh, Dawn H., Kudo, Takashi, Truong, Danny, Wu, Yingfei, Colwell, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728350/
https://www.ncbi.nlm.nih.gov/pubmed/23936129
http://dx.doi.org/10.1371/journal.pone.0069993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728350/
https://www.ncbi.nlm.nih.gov/pubmed/23936129
http://dx.doi.org/10.1371/journal.pone.0069993

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