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Allosteric Inhibitors of the NS3 Protease from the Hepatitis C Virus
The nonstructural protein 3 (NS3) from the hepatitis C virus processes the non-structural region of the viral precursor polyprotein in infected hepatic cells. The NS3 protease activity has been considered a target for drug development since its identification two decades ago. Although specific inhib...
Autores principales: | Abian, Olga, Vega, Sonia, Sancho, Javier, Velazquez-Campoy, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728351/ https://www.ncbi.nlm.nih.gov/pubmed/23936097 http://dx.doi.org/10.1371/journal.pone.0069773 |
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