Exome Sequencing and Linkage Analysis Identified Tenascin-C (TNC) as a Novel Causative Gene in Nonsyndromic Hearing Loss

In this study, a five-generation Chinese family (family F013) with progressive autosomal dominant hearing loss was mapped to a critical region spanning 28.54 Mb on chromosome 9q31.3-q34.3 by linkage analysis, which was a novel DFNA locus, assigned as DFNA56. In this interval, there were 398 annotate...

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Detalles Bibliográficos
Autores principales: Zhao, Yali, Zhao, Feifan, Zong, Liang, Zhang, Peng, Guan, Liping, Zhang, Jianguo, Wang, Dayong, Wang, Jing, Chai, Wei, Lan, Lan, Li, Qian, Han, Bing, Yang, Ling, Jin, Xin, Yang, Weiyan, Hu, Xiaoxiang, Wang, Xiaoning, Li, Ning, Li, Yingrui, Petit, Christine, Wang, Jun, Wang, Huanming Yang Jian, Wang, Qiuju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728356/
https://www.ncbi.nlm.nih.gov/pubmed/23936043
http://dx.doi.org/10.1371/journal.pone.0069549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728356/
https://www.ncbi.nlm.nih.gov/pubmed/23936043
http://dx.doi.org/10.1371/journal.pone.0069549

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