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Downregulation of Steroid Receptor Coactivator-2 Modulates Estrogen-Responsive Genes and Stimulates Proliferation of MCF-7 Breast Cancer Cells

The p160/Steroid Receptor Coactivators SRC-1, SRC-2/GRIP1, and SRC-3/AIB1 are important regulators of Estrogen Receptor alpha (ERα) activity. However, whereas the functions of SRC-1 and SRC-3 in breast tumourigenesis have been extensively studied, little is known about the role of SRC-2. Previously,...

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Detalles Bibliográficos
Autores principales:	Fenne, Ingvild S., Helland, Thomas, Flågeng, Marianne H., Dankel, Simon N., Mellgren, Gunnar, Sagen, Jørn V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728357/ https://www.ncbi.nlm.nih.gov/pubmed/23936147 http://dx.doi.org/10.1371/journal.pone.0070096

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