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Association of Preexisting Drug-Resistance Mutations and Treatment Failure in Hepatitis B Patients

The role of preexisting minority drug-resistance mutations in treatment failure has not been fully understood in chronic hepatitis B patients. To understand mechanisms of drug resistance, we analyzed drug-resistance mutations in 46 treatment-failure patients and in 29 treatment-naïve patients and de...

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Detalles Bibliográficos
Autores principales: Ma, Jie, Zhang, Yingchun, Chen, Xinyue, Jin, Yi, Chen, Dexi, Wu, Yun, Cui, Jing, Wang, Haitao, Liu, Jia, Li, Ning, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728369/
https://www.ncbi.nlm.nih.gov/pubmed/23935839
http://dx.doi.org/10.1371/journal.pone.0067606