Cargando…

Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants

It has been shown that mutations in the WFS1 gene make humans more susceptible to mood disorders. Besides that, mood disorders are associated with alterations in the activity of serotonergic and noradrenergic systems. Therefore, in this study, the effects of imipramine, an inhibitor of serotonin (5-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Visnapuu, Tanel, Raud, Sirli, Loomets, Maarja, Reimets, Riin, Sütt, Silva, Luuk, Hendrik, Plaas, Mario, Kõks, Sulev, Volke, Vallo, Alttoa, Aet, Harro, Jaanus, Vasar, Eero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728556/ https://www.ncbi.nlm.nih.gov/pubmed/23914152 http://dx.doi.org/10.3389/fnins.2013.00132

Ejemplares similares

Male mice with deleted Wolframin (Wfs1) gene have reduced fertility
por: Noormets, Klari, et al.
Publicado: (2009)

Exenatide Is an Effective Antihyperglycaemic Agent in a Mouse Model of Wolfram Syndrome 1
por: Sedman, Tuuli, et al.
Publicado: (2016)

Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration
por: Plaas, Mario, et al.
Publicado: (2017)

Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice
por: Tein, Karin, et al.
Publicado: (2015)

Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile in Wfs1 Knockout Mouse
por: Punapart, Marite, et al.
Publicado: (2014)

Genomics of Wolfram Syndrome 1 (WFS1)
por: Kõks, Sulev
Publicado: (2023)

Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors
por: Tekko, Triin, et al.
Publicado: (2017)

Treatment with the dual-incretin agonist DA-CH5 demonstrates potent therapeutic effect in a rat model of Wolfram Syndrome
por: Jagomäe, Toomas, et al.
Publicado: (2023)

Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model
por: Seppa, Kadri, et al.
Publicado: (2021)

RNA‐sequencing of WFS1‐deficient pancreatic islets
por: Ivask, Marilin, et al.
Publicado: (2016)

GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome
por: Seppa, Kadri, et al.
Publicado: (2019)

Chronic Stress Alters Hippocampal Renin-Angiotensin-Aldosterone System Component Expression in an Aged Rat Model of Wolfram Syndrome
por: Punapart, Marite, et al.
Publicado: (2023)

Analysis of metabolic effects of menthol on WFS1‐deficient mice
por: Ehrlich, Marite, et al.
Publicado: (2016)

Estimating differential expression from multiple indicators
por: Ilmjärv, Sten, et al.
Publicado: (2014)

Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder
por: Traks, Tanel, et al.
Publicado: (2008)

Multiple Retinal Anomalies in Wfs1-Deficient Mice
por: Waszczykowska, Arleta, et al.
Publicado: (2020)

Dopamine System, NMDA Receptor and EGF Family Expressions in Brain Structures of Bl6 and 129Sv Strains Displaying Different Behavioral Adaptation
por: Varul, Jane, et al.
Publicado: (2021)

Trib3 Is Developmentally and Nutritionally Regulated in the Brain but Is Dispensable for Spatial Memory, Fear Conditioning and Sensing of Amino Acid-Imbalanced Diet
por: Örd, Tiit, et al.
Publicado: (2014)

Peptidomic characterization of peptide processing in the hippocampus of Wfs1 knockout mice
por: Tein, Karin, et al.
Publicado: (2015)

Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype
por: Jagomäe, Toomas, et al.
Publicado: (2021)

The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome
por: Punapart, Marite, et al.
Publicado: (2021)

Polymorphisms of IKBKE gene are associated with major depressive disorder and panic disorder
por: Traks, Tanel, et al.
Publicado: (2015)

GLP-1 Receptor Agonists Induce Growth Hormone Secretion in Healthy Volunteers
por: Heinla, Keiu, et al.
Publicado: (2023)

Polymorphisms in Toll-like receptor genes are associated with vitiligo
por: Traks, Tanel, et al.
Publicado: (2015)

The Expression Pattern of Genes Related to Melanogenesis and Endogenous Opioids in Psoriasis
por: Loite, Ulvi, et al.
Publicado: (2021)

Increased Mitochondrial Protein Levels and Bioenergetics in the Musculus Rectus Femoris of Wfs1-Deficient Mice
por: Eimre, Margus, et al.
Publicado: (2018)

Lipopolysaccharide-Induced Strain-Specific Differences in Neuroinflammation and MHC-I Pathway Regulation in the Brains of Bl6 and 129Sv Mice
por: Piirsalu, Maria, et al.
Publicado: (2022)

High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice
por: Kaare, Maria, et al.
Publicado: (2021)

Chronic Alcohol Use Induces Molecular Genetic Changes in the Dorsomedial Thalamus of People with Alcohol-Related Disorders
por: Hade, Andreas-Christian, et al.
Publicado: (2021)

Association of limbic system-associated membrane protein (LSAMP) to male completed suicide
por: Must, Anne, et al.
Publicado: (2008)

Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome
por: Toots, Maarja, et al.
Publicado: (2018)

Hypothermia Alleviates Reductive Stress, a Root Cause of Ischemia Reperfusion Injury
por: Eskla, Kattri-Liis, et al.
Publicado: (2022)

Melanocytes in the Skin – Comparative Whole Transcriptome Analysis of Main Skin Cell Types
por: Reemann, Paula, et al.
Publicado: (2014)

Correction: Melanocytes in the Skin – Comparative Whole Transcriptome Analysis of Main Skin Cell Types
por: Reemann, Paula, et al.
Publicado: (2017)

Depression-Associated Negr1 Gene-Deficiency Induces Alterations in the Monoaminergic Neurotransmission Enhancing Time-Dependent Sensitization to Amphetamine in Male Mice
por: Kaare, Maria, et al.
Publicado: (2022)

VHL-deficiency leads to reductive stress in renal cells
por: Vellama, Hans, et al.
Publicado: (2023)

Promoter-Specific Expression and Genomic Structure of IgLON Family Genes in Mouse
por: Vanaveski, Taavi, et al.
Publicado: (2017)

Gene expression patterns and environmental enrichment-induced effects in the hippocampi of mice suggest importance of Lsamp in plasticity
por: Heinla, Indrek, et al.
Publicado: (2015)

Polymorphisms in IL36G gene are associated with plaque psoriasis
por: Traks, Tanel, et al.
Publicado: (2019)

Wfs1(E864K) knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production
por: Richard, Elodie M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l4ai95h7h0nrak5vmnfmai33jf