High-Resolution Temporal Response Patterns to Influenza Vaccine Reveal a Distinct Human Plasma Cell Gene Signature

To identify sources of inter-subject variation in vaccine responses, we performed high-frequency sampling of human peripheral blood cells post-vaccination, followed by a novel systems biology analysis. Functional principal component analysis was used to examine time varying B cell vaccine responses....

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Detalles Bibliográficos
Autores principales: Henn, Alicia D., Wu, Shuang, Qiu, Xing, Ruda, Melissa, Stover, Michael, Yang, Hongmei, Liu, Zhiping, Welle, Stephen L., Holden-Wiltse, Jeanne, Wu, Hulin, Zand, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728595/
https://www.ncbi.nlm.nih.gov/pubmed/23900141
http://dx.doi.org/10.1038/srep02327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728595/
https://www.ncbi.nlm.nih.gov/pubmed/23900141
http://dx.doi.org/10.1038/srep02327

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