How to switch a master switch

The crystal structure of a nucleotide exchange factor in white blood cells reveals an autoinhibitory mechanism that reinforces the switch-like behaviour of the signalling protein Ras.

Detalles Bibliográficos
Autores principales: Hein, Christopher, Wittinghofer, Alfred, Dötsch, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728619/
https://www.ncbi.nlm.nih.gov/pubmed/23908771
http://dx.doi.org/10.7554/eLife.01159
_version_ 1782278896270442496
author Hein, Christopher
Wittinghofer, Alfred
Dötsch, Volker
author_facet Hein, Christopher
Wittinghofer, Alfred
Dötsch, Volker
author_sort Hein, Christopher
collection PubMed
description The crystal structure of a nucleotide exchange factor in white blood cells reveals an autoinhibitory mechanism that reinforces the switch-like behaviour of the signalling protein Ras.
format Online
Article
Text
id pubmed-3728619
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher eLife Sciences Publications, Ltd
record_format MEDLINE/PubMed
spelling pubmed-37286192013-08-01 How to switch a master switch Hein, Christopher Wittinghofer, Alfred Dötsch, Volker eLife Biophysics and Structural Biology The crystal structure of a nucleotide exchange factor in white blood cells reveals an autoinhibitory mechanism that reinforces the switch-like behaviour of the signalling protein Ras. eLife Sciences Publications, Ltd 2013-07-30 /pmc/articles/PMC3728619/ /pubmed/23908771 http://dx.doi.org/10.7554/eLife.01159 Text en Copyright © 2013, Hein et al http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Biophysics and Structural Biology
Hein, Christopher
Wittinghofer, Alfred
Dötsch, Volker
How to switch a master switch
title How to switch a master switch
title_full How to switch a master switch
title_fullStr How to switch a master switch
title_full_unstemmed How to switch a master switch
title_short How to switch a master switch
title_sort how to switch a master switch
topic Biophysics and Structural Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728619/
https://www.ncbi.nlm.nih.gov/pubmed/23908771
http://dx.doi.org/10.7554/eLife.01159
work_keys_str_mv AT heinchristopher howtoswitchamasterswitch
AT wittinghoferalfred howtoswitchamasterswitch
AT dotschvolker howtoswitchamasterswitch

Ejemplares similares