Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

Eukaryotes have two types of spliceosomes, comprised of either major (U1, U2, U4, U5, U6) or minor (U11, U12, U4atac, U6atac; <1%) snRNPs. The high conservation of minor introns, typically one amidst many major introns in several hundred genes, despite their poor splicing, has been a long-standin...

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Detalles Bibliográficos
Autores principales: Younis, Ihab, Dittmar, Kimberly, Wang, Wei, Foley, Shawn W, Berg, Michael G, Hu, Karen Y, Wei, Zhi, Wan, Lili, Dreyfuss, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728624/
https://www.ncbi.nlm.nih.gov/pubmed/23908766
http://dx.doi.org/10.7554/eLife.00780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728624/
https://www.ncbi.nlm.nih.gov/pubmed/23908766
http://dx.doi.org/10.7554/eLife.00780

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