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Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA
Eukaryotes have two types of spliceosomes, comprised of either major (U1, U2, U4, U5, U6) or minor (U11, U12, U4atac, U6atac; <1%) snRNPs. The high conservation of minor introns, typically one amidst many major introns in several hundred genes, despite their poor splicing, has been a long-standin...
Autores principales: | Younis, Ihab, Dittmar, Kimberly, Wang, Wei, Foley, Shawn W, Berg, Michael G, Hu, Karen Y, Wei, Zhi, Wan, Lili, Dreyfuss, Gideon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728624/ https://www.ncbi.nlm.nih.gov/pubmed/23908766 http://dx.doi.org/10.7554/eLife.00780 |
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