Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications

Lipodystrophy (LD) is a serious complication of highly active anti-retroviral therapy, characterized by peripheral fat wasting, central adiposity and metabolic changes. Since the disfiguration caused by LD is permanent, the focus of management is on early detection to arrest progression. We report a...

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Autores principales: Zade, Anand, Rangarajan, Venkatesh, Purandare, Nilendu, Shah, Sneha, Agrawal, Archi, Jha, Ashish, Kulkarni, Mukta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728741/
https://www.ncbi.nlm.nih.gov/pubmed/23919073
http://dx.doi.org/10.4103/0972-3919.112726
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author Zade, Anand
Rangarajan, Venkatesh
Purandare, Nilendu
Shah, Sneha
Agrawal, Archi
Jha, Ashish
Kulkarni, Mukta
author_facet Zade, Anand
Rangarajan, Venkatesh
Purandare, Nilendu
Shah, Sneha
Agrawal, Archi
Jha, Ashish
Kulkarni, Mukta
author_sort Zade, Anand
collection PubMed
description Lipodystrophy (LD) is a serious complication of highly active anti-retroviral therapy, characterized by peripheral fat wasting, central adiposity and metabolic changes. Since the disfiguration caused by LD is permanent, the focus of management is on early detection to arrest progression. We report a case where ancillary finding of increased fluorine-18 fluoro-2-deoxyglucose (F-18 FDG) uptake in the sub-cutaneous fat helped early detection of LD and led to early intervention to arrest progression. Though F-18 FDG positron emission tomography/computed tomography scan is not recommended to diagnose LD, conscious reporting of this finding when present can greatly influence patient management.
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spelling pubmed-37287412013-08-05 Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications Zade, Anand Rangarajan, Venkatesh Purandare, Nilendu Shah, Sneha Agrawal, Archi Jha, Ashish Kulkarni, Mukta Indian J Nucl Med Case Report Lipodystrophy (LD) is a serious complication of highly active anti-retroviral therapy, characterized by peripheral fat wasting, central adiposity and metabolic changes. Since the disfiguration caused by LD is permanent, the focus of management is on early detection to arrest progression. We report a case where ancillary finding of increased fluorine-18 fluoro-2-deoxyglucose (F-18 FDG) uptake in the sub-cutaneous fat helped early detection of LD and led to early intervention to arrest progression. Though F-18 FDG positron emission tomography/computed tomography scan is not recommended to diagnose LD, conscious reporting of this finding when present can greatly influence patient management. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3728741/ /pubmed/23919073 http://dx.doi.org/10.4103/0972-3919.112726 Text en Copyright: © Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Zade, Anand
Rangarajan, Venkatesh
Purandare, Nilendu
Shah, Sneha
Agrawal, Archi
Jha, Ashish
Kulkarni, Mukta
Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications
title Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications
title_full Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications
title_fullStr Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications
title_full_unstemmed Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications
title_short Hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: Subtle finding with implications
title_sort hypermetabolic subcutaneous fat in patients on highly active anti-retroviral therapy treatment: subtle finding with implications
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728741/
https://www.ncbi.nlm.nih.gov/pubmed/23919073
http://dx.doi.org/10.4103/0972-3919.112726
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