An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling

In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical systems (in-vitro techniques), as well as the proposal and the testing of mathema...

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Detalles Bibliográficos
Autores principales: Lamberti, Gaetano, Cascone, Sara, Titomanlio, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università di Salerno 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728799/
https://www.ncbi.nlm.nih.gov/pubmed/23905061
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author Lamberti, Gaetano
Cascone, Sara
Titomanlio, Giuseppe
author_facet Lamberti, Gaetano
Cascone, Sara
Titomanlio, Giuseppe
author_sort Lamberti, Gaetano
collection PubMed
description In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical systems (in-vitro techniques), as well as the proposal and the testing of mathematical models to describe the pharmacokinetics (in-silico techniques) are reported with the aim of pointing out methodologies and tools able to reduce the need of expensive and ethical problematic in-vivo measurements.
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spelling pubmed-37287992013-07-31 An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling Lamberti, Gaetano Cascone, Sara Titomanlio, Giuseppe Transl Med UniSa Review In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical systems (in-vitro techniques), as well as the proposal and the testing of mathematical models to describe the pharmacokinetics (in-silico techniques) are reported with the aim of pointing out methodologies and tools able to reduce the need of expensive and ethical problematic in-vivo measurements. Università di Salerno 2012-10-11 /pmc/articles/PMC3728799/ /pubmed/23905061 Text en http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Lamberti, Gaetano
Cascone, Sara
Titomanlio, Giuseppe
An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling
title An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling
title_full An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling
title_fullStr An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling
title_full_unstemmed An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling
title_short An Engineering Approach to Biomedical Sciences: Advanced Testing Methods and Pharmacokinetic Modeling
title_sort engineering approach to biomedical sciences: advanced testing methods and pharmacokinetic modeling
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728799/
https://www.ncbi.nlm.nih.gov/pubmed/23905061
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