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Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster

Directional dominance is a prerequisite of inbreeding depression. Directionality arises when selection drives alleles that increase fitness to fixation and eliminates dominant deleterious alleles, while deleterious recessives are hidden from it and maintained at low frequencies. Traits under directi...

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Autores principales: Ala-Honkola, Outi, Hosken, David J, Manier, Mollie K, Lüpold, Stefan, Droge-Young, Elizabeth M, Berben, Kirstin S, Collins, William F, Belote, John M, Pitnick, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728949/
https://www.ncbi.nlm.nih.gov/pubmed/23919154
http://dx.doi.org/10.1002/ece3.625
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author Ala-Honkola, Outi
Hosken, David J
Manier, Mollie K
Lüpold, Stefan
Droge-Young, Elizabeth M
Berben, Kirstin S
Collins, William F
Belote, John M
Pitnick, Scott
author_facet Ala-Honkola, Outi
Hosken, David J
Manier, Mollie K
Lüpold, Stefan
Droge-Young, Elizabeth M
Berben, Kirstin S
Collins, William F
Belote, John M
Pitnick, Scott
author_sort Ala-Honkola, Outi
collection PubMed
description Directional dominance is a prerequisite of inbreeding depression. Directionality arises when selection drives alleles that increase fitness to fixation and eliminates dominant deleterious alleles, while deleterious recessives are hidden from it and maintained at low frequencies. Traits under directional selection (i.e., fitness traits) are expected to show directional dominance and therefore an increased susceptibility to inbreeding depression. In contrast, traits under stabilizing selection or weakly linked to fitness are predicted to exhibit little-to-no inbreeding depression. Here, we quantify the extent of inbreeding depression in a range of male reproductive characters and then infer the mode of past selection on them. The use of transgenic populations of Drosophila melanogaster with red or green fluorescent-tagged sperm heads permitted in vivo discrimination of sperm from competing males and quantification of characteristics of ejaculate composition, performance, and fate. We found that male attractiveness (mating latency) and competitive fertilization success (P(2)) both show some inbreeding depression, suggesting they may have been under directional selection, whereas sperm length showed no inbreeding depression suggesting a history of stabilizing selection. However, despite having measured several sperm quality and quantity traits, our data did not allow us to discern the mechanism underlying the lowered competitive fertilization success of inbred (f = 0.50) males.
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spelling pubmed-37289492013-08-05 Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster Ala-Honkola, Outi Hosken, David J Manier, Mollie K Lüpold, Stefan Droge-Young, Elizabeth M Berben, Kirstin S Collins, William F Belote, John M Pitnick, Scott Ecol Evol Original Research Directional dominance is a prerequisite of inbreeding depression. Directionality arises when selection drives alleles that increase fitness to fixation and eliminates dominant deleterious alleles, while deleterious recessives are hidden from it and maintained at low frequencies. Traits under directional selection (i.e., fitness traits) are expected to show directional dominance and therefore an increased susceptibility to inbreeding depression. In contrast, traits under stabilizing selection or weakly linked to fitness are predicted to exhibit little-to-no inbreeding depression. Here, we quantify the extent of inbreeding depression in a range of male reproductive characters and then infer the mode of past selection on them. The use of transgenic populations of Drosophila melanogaster with red or green fluorescent-tagged sperm heads permitted in vivo discrimination of sperm from competing males and quantification of characteristics of ejaculate composition, performance, and fate. We found that male attractiveness (mating latency) and competitive fertilization success (P(2)) both show some inbreeding depression, suggesting they may have been under directional selection, whereas sperm length showed no inbreeding depression suggesting a history of stabilizing selection. However, despite having measured several sperm quality and quantity traits, our data did not allow us to discern the mechanism underlying the lowered competitive fertilization success of inbred (f = 0.50) males. Blackwell Publishing Ltd 2013-07 2013-06-03 /pmc/articles/PMC3728949/ /pubmed/23919154 http://dx.doi.org/10.1002/ece3.625 Text en © 2013 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
spellingShingle Original Research
Ala-Honkola, Outi
Hosken, David J
Manier, Mollie K
Lüpold, Stefan
Droge-Young, Elizabeth M
Berben, Kirstin S
Collins, William F
Belote, John M
Pitnick, Scott
Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster
title Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster
title_full Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster
title_fullStr Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster
title_full_unstemmed Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster
title_short Inbreeding reveals mode of past selection on male reproductive characters in Drosophila melanogaster
title_sort inbreeding reveals mode of past selection on male reproductive characters in drosophila melanogaster
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728949/
https://www.ncbi.nlm.nih.gov/pubmed/23919154
http://dx.doi.org/10.1002/ece3.625
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