Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563

BACKGROUND: Vibrio fluvialis is an emerging diarrheal pathogen for which no genome is currently available. In this work, draft genomes of two closely related clinical strains PG41 and I21563 have been explored. RESULTS: V. fluvialis strains PG41 and I21563 were sequenced on the Illumina HiSeq 1000 p...

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Autores principales: Khatri, Indu, Mahajan, Sakshi, Dureja, Chetna, Subramanian, Srikrishna, Raychaudhuri, Saumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Genome Announcement
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729366/
https://www.ncbi.nlm.nih.gov/pubmed/23895343
http://dx.doi.org/10.1186/1757-4749-5-20
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author Khatri, Indu
Mahajan, Sakshi
Dureja, Chetna
Subramanian, Srikrishna
Raychaudhuri, Saumya
author_facet Khatri, Indu
Mahajan, Sakshi
Dureja, Chetna
Subramanian, Srikrishna
Raychaudhuri, Saumya
author_sort Khatri, Indu
collection PubMed
description BACKGROUND: Vibrio fluvialis is an emerging diarrheal pathogen for which no genome is currently available. In this work, draft genomes of two closely related clinical strains PG41 and I21563 have been explored. RESULTS: V. fluvialis strains PG41 and I21563 were sequenced on the Illumina HiSeq 1000 platform to obtain draft genomes of 5.3 Mbp and 4.4 Mbp respectively. Our genome data reveal the presence of genes involved in ethanolamine utilization, which is further experimentally confirmed by growth analysis. CONCLUSIONS: Combined in silico and growth analysis establish a new metabolic capacity of V. fluvialis to harvest energy from ethanolamine.
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spelling pubmed-37293662013-08-01 Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563 Khatri, Indu Mahajan, Sakshi Dureja, Chetna Subramanian, Srikrishna Raychaudhuri, Saumya Gut Pathog Genome Announcement BACKGROUND: Vibrio fluvialis is an emerging diarrheal pathogen for which no genome is currently available. In this work, draft genomes of two closely related clinical strains PG41 and I21563 have been explored. RESULTS: V. fluvialis strains PG41 and I21563 were sequenced on the Illumina HiSeq 1000 platform to obtain draft genomes of 5.3 Mbp and 4.4 Mbp respectively. Our genome data reveal the presence of genes involved in ethanolamine utilization, which is further experimentally confirmed by growth analysis. CONCLUSIONS: Combined in silico and growth analysis establish a new metabolic capacity of V. fluvialis to harvest energy from ethanolamine. BioMed Central 2013-07-29 /pmc/articles/PMC3729366/ /pubmed/23895343 http://dx.doi.org/10.1186/1757-4749-5-20 Text en Copyright © 2013 Khatri et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Genome Announcement
Khatri, Indu
Mahajan, Sakshi
Dureja, Chetna
Subramanian, Srikrishna
Raychaudhuri, Saumya
Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563
title Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563
title_full Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563
title_fullStr Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563
title_full_unstemmed Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563
title_short Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563
title_sort evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of vibrio fluvialis strains pg41 and i21563
topic Genome Announcement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729366/
https://www.ncbi.nlm.nih.gov/pubmed/23895343
http://dx.doi.org/10.1186/1757-4749-5-20
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