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Study protocol of Prednisone in episodic Cluster Headache (PredCH): a randomized, double-blind, placebo-controlled parallel group trial to evaluate the efficacy and safety of oral prednisone as an add-on therapy in the prophylactic treatment of episodic cluster headache with verapamil
BACKGROUND: Episodic cluster headache (ECH) is a primary headache disorder that severely impairs patient’s quality of life. First-line therapy in the initiation of a prophylactic treatment is verapamil. Due to its delayed onset of efficacy and the necessary slow titration of dosage for tolerability...
Autores principales: | Holle, Dagny, Burmeister, Jan, Scherag, André, Ose, Claudia, Diener, Hans-Christoph, Obermann, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729502/ https://www.ncbi.nlm.nih.gov/pubmed/23889923 http://dx.doi.org/10.1186/1471-2377-13-99 |
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