FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

BACKGROUND: The Sphingosine-1-phosphate (S1P) signaling pathway is known to influence pathophysiological processes within the brain and the synthetic S1P analog FTY720 has been shown to provide neuroprotection in experimental models of acute stroke. However, the effects of a manipulation of S1P sign...

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Detalles Bibliográficos
Autores principales: Brunkhorst, Robert, Kanaan, Nathalie, Koch, Alexander, Ferreirós, Nerea, Mirceska, Ana, Zeiner, Pia, Mittelbronn, Michel, Derouiche, Amin, Steinmetz, Helmuth, Foerch, Christian, Pfeilschifter, Josef, Pfeilschifter, Waltraud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729514/
https://www.ncbi.nlm.nih.gov/pubmed/23936150
http://dx.doi.org/10.1371/journal.pone.0070124

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